Multiple Sclerosis/*complications

Conversion of PASAT3 scores into SDMT scores for cognitive research in people with multiple sclerosis.
BACKGROUND: Due to the prevalence and impact of cognitive impairment on quality of life, regular screening for changes in cognition is …
Caroline Hamal, Matthias Grothe, Stefan Gross, Johan Baijot, Jeroen Van Schependom, Frederik Van de Steen, Iris-Katharina Penner, Guy Nagels
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Lost in dichotomization: Preserving statistical power and sensitivity in MS cognitive research.
BACKGROUND: Research on cognitive impairment in multiple sclerosis (MS) often reduces performance across diverse domains-such as …
Jeroen Van Schependom, Gary Cutter
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A New Smartphone-Based Cognitive Screening Battery for Multiple Sclerosis (icognition): Validation Study.
BACKGROUND: Cognitive deterioration is common in multiple sclerosis (MS) and requires regular follow-up. Currently, cognitive status is …
Stijn Denissen, Delphine Van Laethem, Johan Baijot, Lars Costers, Annabel Descamps, Ann Van Remoortel, Annick Van Merhaegen-Wieleman, Marie D'hooghe, Miguel D'haeseleer, Dirk Smeets, Diana M. Sima, Jeroen Van Schependom, Guy Nagels
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The spectral slope as a marker of excitation/inhibition ratio and cognitive functioning in multiple sclerosis.
Multiple sclerosis (MS) is a neurodegenerative disease characterized by neuronal and synaptic loss, resulting in an imbalance of …
Fahimeh Akbarian, Chiara Rossi, Lars Costers, Marie B. D'hooghe, Miguel D'haeseleer, Guy Nagels, Jeroen Van Schependom
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The spectral slope as a marker of excitation/inhibition ratio and cognitive functioning in multiple sclerosis.
Reduced alpha2 power is associated with slowed information processing speed in multiple sclerosis.
OBJECTIVE: Cognitive impairment is common in multiple sclerosis (MS), significantly impacts daily functioning, is time-consuming to …
Alexander De Cock, Alexander Van Ranst, Lars Costers, Eva Keytsman, Marie B. D'hooghe, Miguel D'haeseleer, Guy Nagels, Jeroen Van Schependom
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Brain age as a surrogate marker for cognitive performance in multiple sclerosis.
BACKGROUND AND PURPOSE: Data from neuro-imaging techniques allow us to estimate a brain’s age. Brain age is easily interpretable …
Stijn Denissen, Denis Alexander Engemann, Alexander De Cock, Lars Costers, Johan Baijot, Jorne Laton, Iris-Katharina Penner, Matthias Grothe, Michael Kirsch, Marie Beatrice D'hooghe, Miguel D'haeseleer, Dominique Dive, Johan De Mey, Jeroen Van Schependom, Diana Maria Sima, Guy Nagels
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The role of hippocampal theta oscillations in working memory impairment in multiple sclerosis.
Working memory (WM) problems are frequently present in people with multiple sclerosis (MS). Even though hippocampal damage has been …
Lars Costers, Jeroen Van Schependom, Jorne Laton, Johan Baijot, Martin Sjøgård, Vincent Wens, Xavier De Tiège, Serge Goldman, Miguel D'haeseleer, Marie Beatrice D'hooghe, Mark Woolrich, Guy Nagels
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The role of hippocampal theta oscillations in working memory impairment in multiple sclerosis.
Brain dysconnectivity relates to disability and cognitive impairment in multiple sclerosis.
The pathophysiology of cognitive dysfunction in multiple sclerosis (MS) is still unclear. This magnetoencephalography (MEG) study …
Martin Sjøgård, Vincent Wens, Jeroen Van Schependom, Lars Costers, Marie D'hooghe, Miguel D'haeseleer, Mark Woolrich, Serge Goldman, Guy Nagels, Xavier De Tiège
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Reduced information processing speed as primum movens for cognitive decline in MS.
BACKGROUND: Cognitive impairment affects half of the multiple sclerosis (MS) patient population and is an important contributor to …
Jeroen Van Schependom, Marie B. D'hooghe, Krista Cleynhens, Mieke D'hooge, Marie-Claire Haelewyck, Jacques De Keyser, Guy Nagels
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The Symbol Digit Modalities Test as sentinel test for cognitive impairment in multiple sclerosis.
BACKGROUND AND PURPOSE: Cognitive impairment (CI) is found in about half of the multiple sclerosis (MS) population and is an important …
J. Van Schependom, M. B. D'hooghe, K. Cleynhens, M. D'hooge, M. C. Haelewyck, J. De Keyser, G. Nagels
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The Symbol Digit Modalities Test as sentinel test for cognitive impairment in multiple sclerosis.