Nerve Net/physiopathology

Temporally Defined Brain Network Activation Associated With Slowed Information Processing Speed in Multiple Sclerosis.

Information processing speed (IPS) is a core cognitive deficit in people with multiple sclerosis (PwMS). Previous efforts have …

Olivier Burta, Fahimeh Akbarian, Chiara Rossi, Diego Vidaurre, Marie Bie D'hooghe, Miguel D'haeseleer, Guy Nagels, Jeroen Van Schependom

Disrupted working memory event-related network dynamics in multiple sclerosis.

In multiple sclerosis (MS), working memory (WM) impairment can occur soon after disease onset and significantly affects the …

Chiara Rossi, Diego Vidaurre, Lars Costers, Marie B. D'hooghe, Fahimeh Akbarian, Miguel D'haeseleer, Mark Woolrich, Guy Nagels, Jeroen Van Schependom

Signal quality as Achilles' heel of graph theory in functional magnetic resonance imaging in multiple sclerosis.

Graph-theoretical analysis is a novel tool to understand the organisation of the brain.We assessed whether altered graph theoretical …

Johan Baijot, Stijn Denissen, Lars Costers, Jeroen Gielen, Melissa Cambron, Miguel D'haeseleer, Marie B. D'hooghe, Anne-Marie Vanbinst, Johan De Mey, Guy Nagels, Jeroen Van Schependom

Brain dysconnectivity relates to disability and cognitive impairment in multiple sclerosis.

The pathophysiology of cognitive dysfunction in multiple sclerosis (MS) is still unclear. This magnetoencephalography (MEG) study …

Martin Sjøgård, Vincent Wens, Jeroen Van Schependom, Lars Costers, Marie D'hooghe, Miguel D'haeseleer, Mark Woolrich, Serge Goldman, Guy Nagels, Xavier De Tiège

Graph theoretical analysis indicates cognitive impairment in MS stems from neural disconnection.

BACKGROUND: The mechanisms underlying cognitive impairment in MS are still poorly understood. However, due to the specific pathology of …

Jeroen Van Schependom, Jeroen Gielen, Jorne Laton, Marie B. D'hooghe, Jacques De Keyser, Guy Nagels